Publications

  • Moretti, B. Jia, Z. Hutchins, S. Roy, H. Yip, J. Wu, M. Shan, S.R. Jaffrey, J. Coers, J.M. Blander, “Caspase-11 interaction with NLRP3 potentiates the noncanonical activation of the NLRP3 inflammasome”, Nature Immunology, 2022, in press.
  • J. Wu*, N. Svenson*, W. Song, H. Kim, S. Zhang, X. Li, S.R. Jaffrey, “Genetically Encoded Multivalent RNA Complexes in Mammalian Cells Templated by Corn and Beetroot”, Journal of the American Chemical Society, 2022, 144, 5471. (*Contributed equally)
  • B.S. VarnBuhler*, J. Moon*, S.K. Dey, J. Wu, S.R. Jaffrey, “Detection of SARS-CoV-2 RNA using a DNA Aptamer Mimic of Green Fluorescent Protein”, ACS Chemical Biology, 2022, 17, 840. (*Contributed equally)
  • J. Wu, S.R. Jaffrey, “Live-cell Imaging of mRNA Using a Pepper RNA Tag”, Methods in Molecular Biology, 2022, in press.
  • X. Li, J. Wu, S.R. Jaffrey, “Engineering Fluorophore Recycling in a Fluorogenic RNA Aptamer”, Angewandte Chemie, 2021, 60, 24153–24161.
  • J.D. Moon, J. Wu, S.K. Dey, J.L. Litke, H. Kim, S.R. Jaffrey, “Naturally Occurring Three-way Junctions Can be Repurposed as Genetically Encoded RNA-based Sensors”, Cell Chemical Biology, 2021, 28, 1569–1580.
  • L. Tang, S. Zhang, Y. Zhao, N.D. Rozanov, L. Zhu, J. Wu, R.E. Campbell, C. Fang, “Switching between Ultrafast Pathways Enables a Green-Red Emission Ratiometric Fluorescent-Protein-Based Ca2+ Biosensor”, International Journal of Molecular Sciences, 2021, 22, 445.
  • R. Dalangin, M. Drobizhev, R.S. Molina, A. Aggarwal, R. Patel, A.S. Abdelfattah, Y. Zhao, J. Wu, K. Podgorski, E.R. Schreiter, T.E. Hughes, R.E. Campbell, Y. Shen, “Far-red Fluorescent Genetically Encoded Calcium Ion Indicators”, bioRxiv, 2020.
  • J. Wu, S.R. Jaffrey, “Imaging mRNA Trafficking in Living Cells Using Fluorogenic Proteins”, Current Opinion in Chemical Biology, 2020, 57, 177–183.
  • X. Li, H. Kim, J.L. Litke, J. Wu, S.R. Jaffrey, “Fluorophore-promoted RNA Folding and Photostability Enable Imaging of Single Broccoli-tagged mRNAs in Live Mammalian Cells”, Angewandte Chemie, 2020, 59, 4511–4518.
  • J. Wu, S. Zaccara, D. Khuperkar, H. Kim, M.E. Tanenbaum, S.R. Jaffrey, “Live Imaging of mRNA Using RNA-stabilized Fluorogenic Proteins”, Nature Methods, 2019, 16, 862–865.
  • R.S. Molina, Y. Qian, J. Wu, Y. Shen, R.E. Campbell, T.E. Hughes, M. Drobizhev, “Understanding the Ca2+-dependent Fluorescence Change in Red Genetically Encoded Ca2+ Indicators”, Biophysical Journal, 2019, 116, 1873–1886.
  • Y. Qian, K.D. Piatkevich, B. Mc Larney, A.S. Abdelfattah, S. Mehta, M.H. Murdock, S. Gottschalk, R.S. Molina, W. Zhang, Y. Chen, J. Wu, M. Drobizhev, T.E. Hughes, J. Zhang, E.R. Schreiter, S. Shoham, D. Razansky, E.S. Boyden, R.E. Campbell, “A Genetically Encoded Near-infrared Fluorescent Calcium Ion Indicator”, Nature Methods, 2019, 16, 171–174.
  • Y. Qian, V. Rancic, J. Wu, K. Ballanyi, R.E. Campbell, “A Bioluminescent Ca2+ Indicator Based on a Topological Variant of GCaMP6s”, ChemBioChem, 2019, 20, 516–520.
  • J. Wu, A.S. Abdelfattah, H. Zhou, A. Ruangkittisakul, Y. Qian, K. Ballanyi, R.E. Campbell, “Genetically Encoded Glutamate Indicators with Altered Color and Topology”, ACS Chemical Biology, 2018, 13, 1832–1837.
  • Y. Shen, Y. Chen, J. Wu, N.C. Shaner, R. E. Campbell, “Engineering of mCherry Variants with Long Stokes Shift, Red-shifted Fluorescence, and Low Cytotoxicity”, PloS One, 2017, 12, e0171257.
  • J. Wu, S.R. Jaffrey, “Tracking Translation One mRNA at a Time”, Nature Biotechnology, 2016, 34, 723–724.
  • Y. Li*, A. Forbrich*, J. Wu, P. Shao, R.E. Campbell, R. Zemp, “Engineering Dark Chromoprotein Reporters for Photoacoustic Microscopy and FRET Imaging”, Scientific Reports, 2016, 6, 22129. (*Contributed equally)
  • J. Wu, A.S. Abdelfattah, E. Kutsarova, L.S. Miraucourt, A. Ruangkittisakul, H. Zhou, K. Ballanyi, G. Wicks, M. Drobizhev, E.S. Ruthazer, R.E. Campbell, “A Long Stokes Shift Red Fluorescent Ca2+ Indicator Protein for Two-photon and Ratiometric Imaging”, Nature Communications, 2014, 5, 5262.
  • J. Wu, D.L. Prole, Y. Shen, Z. Lin, A. Gnanasekaran, Y. Liu, L. Chen, H. Zhou, S.R.W. Chen, Y. Usachev, C.W. Taylor, R.E. Campbell, “Red Fluorescent Genetically Encoded Ca2+ Indicators for Use in Mitochondria and Endoplasmic Reticulum”, Biochemical Journal, 2014, 464, 13–22.
  • E.M. Lynes, A. Raturi, M. Shenkman, C.O. Sandoval, M.C. Yap, J. Wu, A. Janowicz, N. Myhill, M.D. Benson, R.E. Campbell, L.G. Berthiaume, G.Z. Lederkremer, T. Simmen, “Palmitoylation is the Switch that Assigns Calnexin to Quality Control or ER Calcium Signaling”, Journal of Cell Science, 2013, 126, 3893–3903.
  • J. Wu, L. Liu, T. Matsuda, Y. Zhao, A. Rebane, M. Drobizhev, Y-F. Chang, S. Araki, Y. Arai, K. March, T.E. Hughes, K. Sagou, T. Miyata, T. Nagai, W-H. Li, R.E. Campbell, “Improved Orange and Red Ca2+ Indicators and Photophysical Considerations for Optogenetic Applications”, ACS Chemical Neuroscience, 2013, 4, 963-972.
  • S.C. Alford, J. Wu, Y. Zhao, R.E. Campbell, T. Knöpfel, “Optogenetic Reporters”, Biology of the Cell, 2013, 105, 14–29.
  • Y. Zhao, S. Araki, J. Wu, T. Teramoto, Y-F. Chang, M. Nakano, A.S. Abdelfattah, M. Fujiwara, T. Ishihara, T. Nagai, R.E. Campbell, “An Expanded Palette of Genetically Encoded Ca2+ Indicators”, Science, 2011, 333, 1888–1891.